BONE & JOINT DISORDERS (ARTHRITIS)

 

ANKYLOSING SPONDYLITIS – RISK FACTORS

 

  • Genetic factors predisposes the disease; it is thought to be inherited as an autosomal dominant trait associated with thepresence of HLA B 27 gene; but it alone is not responsible.

 

  • Age : More common in early adulthood (before 40 years), although young males may have symptoms in adolescent or occasionally in childhood.

 

  • Sex : It is three times more common in males. In females joints away from the spine are more frequently affected.