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Acellular Pertussis Vaccine

Due to the relatively high incidence of side effects with the Pertussis part of DPT vaccine, attempts were made to modify the Pertussis vaccine and reduce the side effects. A new vaccine called ‘Acellular’ Pertussis Vaccine (DTaP) was developed ( “a” in DTaP stands for acellular, which means there are no whole bacteria in the vaccine).

The DPT contains the whole, inactivated pertussis bacteria, while theDTaP uses only the parts of the bacteria, that help children develop immunity to it.


  • It is much better tolerated than DPT. Most of the side effectsattributed to DPT vaccine are much less common with this vaccine.
  • This vaccine is slightly more effective than the traditional DPT vaccine