Latent Autoimmune Diabetes in Adults

Following are the important characteristics of Latent Autoimmune Diabetes in Adults:

  • It is a variation of type 1 diabetes which presents as type 2 diabetes.
  • Patients may show moderate to severe symptoms.
  • Fasting Plasma Glucose more than 300mg/dl.
  • Body Mass Index (BMI) less than 19.
  • No family history of Diabetes.
  • Presence of  “Glutamic Acid Decarboxylase” antibodies in blood, indicating autoimmune damage to Pancreas (autoimmune insulitis).
  • The importance of recognizing such patients is important because they may be mistaken to be candidates for oral hypoglycemic drugs. Use of sulphonylureas may in fact, worsen the condition by accelerating the autoimmune damage (due to increased leakage of antigens).
  • Since, LADA is actually a variation of Type 1 Diabetes, regular administration of insulin is required.