It is a monoclonal antibody, usually given to treat acute rejection of kidneys when steroid therapy fails.
- Action
- Large doses of Muromonab treat acute rejection of kidney by removing the T cells (responsible for the immune reaction) from the circulation.
- How to take
- Muromonab-CD3 is available in liquid form and is given by injection.
- Precautions
- Avoid driving, operating machinery or other activities requiring mental alertness while taking Muromonab-CD3.
- Side effects
- Fever
- Pain in muscles (myalgia)
- Difficulty in breathing
- Aseptic meningitis
- Increased risk for infection especially cytomegalovirus infection