It is a monoclonal antibody, usually given to treat acute rejection of kidneys when steroid therapy fails.

  • Action
    • Large doses of Muromonab treat acute rejection of kidney by removing the T cells (responsible for the immune reaction) from the circulation.
  • How to take
    • Muromonab-CD3 is available in liquid form and is given by injection.
  • Precautions
    • Avoid driving, operating machinery or other activities requiring mental alertness while taking Muromonab-CD3.
  • Side effects
    • Fever
    • Pain in muscles (myalgia)
    • Difficulty in breathing
    • Aseptic meningitis
    • Increased risk for infection especially cytomegalovirus infection