GRAVE’S DISEASE – What causes Grave’s disease

Graves disease is an autoimmune disorder which is believed to be caused by an antibody that stimulates the thyroid to produce excess thyroid hormone. Technically, some of the body’s lymphocytes (blood cells that participate in immune defense) start producing IgG antibodies which binds to the Thyroid stimulating hormone (TSH) receptor in the thyroid cell causing overproduction of thyroid hormones. These antibodies are called thyroid stimulating immunoglobulin or TSH-receptor antibodies (TRAb) and can be detected in the blood.