Silent thyroiditis (lymphocytic thyroiditis) is a condition characterized by painless thyroid enlargement. As pain and tenderness are absent, it is also called painless thyroiditis. This disease resembles Subacute thyroiditis in some ways and Hashimoto’s (chronic) thyroiditis in others.
It may resemble Subacute thyroiditis in that it
- is also associated with transient (temporary) and self-limited hyperthyroidism
- shows low radioactive iodine uptake in thyroid function tests. It helps in distinguishing painless thyroiditis from Grave’s disease (which shows increased radioactive iodine uptake)
It may resemble Hashimoto’s thyroiditis in that it
- involves lymphocytic infiltration (histopathological feature) of the thyroid.
- may show presence of Antithyroid antibodies in the blood, but the titers are lower as compared to Hashimoto’s thyroiditis.