What really causes Systemic Lupus Erythematosus is not known but it is believed that their are certain factors that may make the immune system overactive, causing the symptoms. These include :


  • Genetic factors : Systemic lupus erythematosus tends to run in families.
  • Environmental factors : Exposure to sunlight may cause flaring (increasing of symptoms) up of the disease.
  • Age : More common in females between the age of 15 and 40.
  • Sex : Females are nine times more prone to develop SLE as compared to males. Sex incidence is more equal in children and elderly.
  • Drugs (Drug induced SLE) : SLE may be triggered by certain drugs which you may be taking for treatment of some other disease. Some of the drugs include chlorpromazine, hydralazine, isoniazid, methyldopa, procainamide and quinidine.
  • Hormonal : It is believed that estrogen in some degree is related to causing the disease as disease aggravation (worsening) has been seen to be commonly occurring during pregnancy and puerperium (six week period following childbirth). Increased incidence has also been seen in fertile women and those taking oral contraceptives.
  • Emotional factor According to Homeopathy a person who worry constantly or those who are under much mental stress have a tendency to develop this disease.